RING1 anticorps (AA 6-387) (Fluoro647)

N° du produit ABIN8033161

Cet anticorps anti-RING1 Polyclonal Lapin conjugué à Fluoro647 (ABIN8033161) détecte spécifiquement RING1 dans FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour RING1 anticorps (AA 6-387) (Fluoro647) (ABIN8033161)

Antigène: RING1 (Ring Finger Protein 1 (RING1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RING1 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-RING1 anticorps (Fluoro647)

Épitope: AA 6-387

Fonction: Anti-RING1 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human RING1 shares 96.3%,96.6% amino acid (aa) sequence identity with mouse,rat RING1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RING1 recombinant protein (Position: N6-K387). Human RING1 shares 96.3% and 96.6% amino acid (aa) sequence identity with mouse and rat RING1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RING1

Antigène: RING1 (Ring Finger Protein 1 (RING1))

Autre désignation: RING1

Sujet:

Background: E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene. This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Gene Full Name: ring finger protein 1

ID gène: 6015

UniProt: Q06587