RNF20 anticorps (AA 123-389) (Fluoro647)

N° du produit ABIN8033260

Cet anticorps anti-RNF20 Monoclonal Souris conjugué à Fluoro647 (Clone 3C6E2) (ABIN8033260) détecte spécifiquement RNF20 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RNF20 anticorps (AA 123-389) (Fluoro647) (ABIN8033260)

Antigène: RNF20 (Ring Finger Protein 20 (RNF20))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RNF20 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Clone: 3C6E2

Détail du produit anti-RNF20 anticorps (Fluoro647)

Épitope: AA 123-389

Fonction: Anti-RNF20 Antibody (monoclonal, 3C6E2) Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RNF20 recombinant protein (Position: E123-S389).

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RNF20

Antigène: RNF20 (Ring Finger Protein 20 (RNF20))

Autre désignation: RNF20

Sujet:

Background: E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene. The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).

Gene Full Name: ring finger protein 20

ID gène: 56254

UniProt: Q5VTR2