Secretin anticorps (AA 25-65) (HRP)

N° du produit ABIN8035203

L’anticorps anti-Secretin Polyclonal Lapin est utilisé pour la détection de Secretin dans des échantillons de Souris et Rat. Il a été validé pour IHC, ELISA et WB.

Aperçu rapide pour Secretin anticorps (AA 25-65) (HRP) (ABIN8035203)

Antigène: Secretin (SECR)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Secretin est conjugé à/à la HRP

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Détail du produit anti-Secretin anticorps (HRP)

Épitope: AA 25-65

Fonction: Anti-Secretin/Sct Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Secretin/Sct recombinant protein (Position: A25-D65).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Secretin

Antigène: Secretin (SECR)

Autre désignation: Sct

Sujet:

Background: Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver. It is a peptide hormone produced in the S cells of the duodenum, which are located in the intestinal glands. In humans, the secretin peptide is encoded by the SCT gene. This gene encodes the precursor of a gastrointestinal peptide hormone of the secretin-glucagon family. The encoded protein is secreted as a prohormone that undergoes proteolytic processing to generate a mature peptide hormone. The mature peptide regulates secretion of gastric acid, biocarbonate ions from pancreatic and biliary duct epithelia and water homeostasis in the gastrointestinal system. Mice lacking the encoded protein display decreased survival of neuroprogenitor cells during early postnatal period and impaired long-term potentiation and spatial learning in adulthood. Alternative splicing results in multiple transcript variants encoding different isoforms. All of these isoforms may be processed in a similar manner to generate the mature peptide hormone.

Gene Full Name: secretin

ID gène: 20287

UniProt: Q08535

Pathways: Stem Cell Maintenance