Secretin anticorps (AA 25-65) (APC)

N° du produit ABIN8035204

Cet anticorps anti-Secretin Polyclonal Lapin conjugué à APC (ABIN8035204) détecte spécifiquement Secretin dans FACS. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour Secretin anticorps (AA 25-65) (APC) (ABIN8035204)

Antigène: Secretin (SECR)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Secretin est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-Secretin anticorps (APC)

Épitope: AA 25-65

Fonction: Anti-Secretin/Sct Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Secretin/Sct recombinant protein (Position: A25-D65).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Secretin

Antigène: Secretin (SECR)

Autre désignation: Sct

Sujet:

Background: Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver. It is a peptide hormone produced in the S cells of the duodenum, which are located in the intestinal glands. In humans, the secretin peptide is encoded by the SCT gene. This gene encodes the precursor of a gastrointestinal peptide hormone of the secretin-glucagon family. The encoded protein is secreted as a prohormone that undergoes proteolytic processing to generate a mature peptide hormone. The mature peptide regulates secretion of gastric acid, biocarbonate ions from pancreatic and biliary duct epithelia and water homeostasis in the gastrointestinal system. Mice lacking the encoded protein display decreased survival of neuroprogenitor cells during early postnatal period and impaired long-term potentiation and spatial learning in adulthood. Alternative splicing results in multiple transcript variants encoding different isoforms. All of these isoforms may be processed in a similar manner to generate the mature peptide hormone.

Gene Full Name: secretin

ID gène: 20287

UniProt: Q08535

Pathways: Stem Cell Maintenance