SEZ6L anticorps (AA 662-953) (Fluoro488)

N° du produit ABIN8035276

Cet anticorps anti-SEZ6L Polyclonal Lapin conjugué à Fluoro488 (ABIN8035276) détecte spécifiquement SEZ6L dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SEZ6L anticorps (AA 662-953) (Fluoro488) (ABIN8035276)

Antigène: SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEZ6L est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-SEZ6L anticorps (Fluoro488)

Épitope: AA 662-953

Fonction: Anti-SEZ6L Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SEZ6L recombinant protein (Position: E662-E953).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SEZ6L

Antigène: SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))

Autre désignation: SEZ6L

Sujet:

Background: Seizure 6-like protein is a protein that in humans is encoded by the SEZ6L gene. SEZ6L (Seizure 6-Like protein, also BSRP-B in rodent) is a 200 kDa member of the SEZ6 family of proteins. It is expressed in the plasma membrane and ER of CNS neurons and lung bronchiolar epithelium, and likely regulates PKC alpha activation. Mature human SEZ6L is a 996 amino acid (aa) type I transmembrane protein. It contains a 930 aa extracellular domain (ECD) (aa 29-958) plus a 45 aa cytoplasmic tail. The ECD shows three CUB domains and five short consensus repeats (SCRs). There are multiple isoforms possible for SEZ6L. One shows a deletion of aa 933-943, and a second shows the same deletion coupled to a Thr substitution for aa 803-867. A third isoform contains a Leu substitution for aa 867-943. An alternative start site is reported at Met228. This start site may occur individually, or be accompanied by a deletion of aa 932-944, the same deletion of aa 932-944 coupled to a Thr substitution for aa 803-867, or a duel deletion of aa 869-945 and 1016-1024. Over aa 29-958, human BSRP-B is 80 % aa identical to mouse BSRP-B.

Gene Full Name: seizure related 6 homolog like

ID gène: 23544

UniProt: Q9BYH1