L-Selectin anticorps (AA 39-372) (Fluoro488)

N° du produit ABIN8035320

L’anticorps anti-L-Selectin Polyclonal Lapin est utilisé pour la détection de L-Selectin dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour L-Selectin anticorps (AA 39-372) (Fluoro488) (ABIN8035320)

Antigène: L-Selectin (SELL) (Selectin L (SELL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L-Selectin est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-L-Selectin anticorps (Fluoro488)

Épitope: AA 39-372

Fonction: Anti-CD62L/SELL Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 %,78.7 % amino acid (aa) sequence identity with mouse,rat L-selectin,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 % and 78.7 % amino acid (aa) sequence identity with mouse and rat L-selectin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur L-Selectin

Antigène: L-Selectin (SELL) (Selectin L (SELL))

Autre désignation: SELL

Sujet:

Background: CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a homing receptor for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

Gene Full Name: selectin L

Sequence Similarities: Belongs to the selectin/LECAM family.

ID gène: 6402

UniProt: P14151