SELPLG anticorps (AA 18-397) (Fluoro488)

N° du produit ABIN8035386

L’anticorps anti-SELPLG Polyclonal Lapin est utilisé pour la détection de SELPLG dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour SELPLG anticorps (AA 18-397) (Fluoro488) (ABIN8035386)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SELPLG est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-SELPLG anticorps (Fluoro488)

Épitope: AA 18-397

Fonction: Anti-PSGL-1/Selplg Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse PSGL-1/Selplg recombinant protein (Position: L18-P397).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: Selplg

Sujet:

Background: Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162), is a human gene. It is mapped to 5 F, 5 55.59 cM. This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

Gene Full Name: selectin, platelet (p-selectin) ligand

ID gène: 20345

UniProt: Q62170