STK4 anticorps (AA 324-452) (HRP)

N° du produit ABIN8036132

Cet anticorps Lapin Polyclonal détecte spécifiquement STK4 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour STK4 anticorps (AA 324-452) (HRP) (ABIN8036132)

Antigène: STK4 (serine/threonine Kinase 4 (STK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK4 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-STK4 anticorps (HRP)

Épitope: AA 324-452

Fonction: Anti-MST1/STK4 Antibody HRP Conjugated

Homologie: Human STK4 shares 93.8% amino acid (aa) sequence identity with mouse STK4.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MST1/STK4 recombinant protein (Position: E324-D452). Human STK4 shares 93.8% amino acid (aa) sequence identity with mouse STK4.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur STK4

Antigène: STK4 (serine/threonine Kinase 4 (STK4))

Autre désignation: MST1/STK4

Sujet:

Background: Serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the STK4 gene. The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Gene Full Name: serine/threonine kinase 4

ID gène: 6789

UniProt: Q13043

Pathways: Tube Formation