SERPINH1 anticorps (AA 247-418) (Fluoro594)

N° du produit ABIN8036285

Cet anticorps Lapin Polyclonal détecte spécifiquement SERPINH1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SERPINH1 anticorps (AA 247-418) (Fluoro594) (ABIN8036285)

Antigène: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINH1 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-SERPINH1 anticorps (Fluoro594)

Épitope: AA 247-418

Fonction: Anti-Hsp47/SERPINH1 Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Hsp47 shares 97% amino acid (aa) sequence identity with both mouse,rat Hsp47.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Hsp47 recombinant protein (Position: D247-L418). Human Hsp47 shares 97% amino acid (aa) sequence identity with both mouse and rat Hsp47.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SERPINH1

Antigène: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Autre désignation: SERPINH1

Sujet:

Background: Heat shock protein 47, also known as SERPINH1 or HSP47, is a serpin which serves as a human chaperone protein for collagen. This protein is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen, thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and, when absent, the rate of transit from the ER to the Golgi is increased and the helical structure is compromised.

Gene Full Name: serpin family H member 1

Sequence Similarities: Belongs to the serpin family.

ID gène: 871

UniProt: P50454