STAP1 anticorps (AA 2-282) (PE)

N° du produit ABIN8037570

L’anticorps anti-STAP1 Polyclonal Lapin est utilisé pour la détection de STAP1 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour STAP1 anticorps (AA 2-282) (PE) (ABIN8037570)

Antigène: STAP1 (Signal Transducing Adaptor Family Member 1 (STAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAP1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-STAP1 anticorps (PE)

Épitope: AA 2-282

Fonction: Anti-STAP-1/STAP1 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human STAP-1/STAP1 recombinant protein (Position: M2-E282).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur STAP1

Antigène: STAP1 (Signal Transducing Adaptor Family Member 1 (STAP1))

Autre désignation: STAP1

Sujet:

Background: Signal-transducing adaptor protein 1 is a protein that in humans is encoded by the STAP1 gene. The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants.

Gene Full Name: signal transducing adaptor family member 1

ID gène: 26228

UniProt: Q9ULZ2