SAP130 anticorps (AA 309-913) (APC)

N° du produit ABIN8037680

Cet anticorps Lapin Polyclonal détecte spécifiquement SAP130 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SAP130 anticorps (AA 309-913) (APC) (ABIN8037680)

Antigène: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAP130 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-SAP130 anticorps (APC)

Épitope: AA 309-913

Fonction: Anti-SAP130 Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SAP130 recombinant protein (Position: H309-H913).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SAP130

Antigène: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Autre désignation: SAP130

Sujet:

Background: Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene. This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

Gene Full Name: Sin3A associated protein 130

ID gène: 79595

UniProt: Q9H0E3