SIRT4 anticorps (C-Term) (Biotin)

N° du produit ABIN8037805

Cet anticorps anti-SIRT4 Polyclonal Lapin conjugué à Biotin (ABIN8037805) détecte spécifiquement SIRT4 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SIRT4 anticorps (C-Term) (Biotin) (ABIN8037805)

Antigène: SIRT4 (Sirtuin 4 (SIRT4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT4 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-SIRT4 anticorps (Biotin)

Épitope: C-Term

Fonction: Anti-SIRT4 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SIRT4, which shares 93.1% amino acid (aa) sequence identity with both mouse and rat SIRT4.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SIRT4

Antigène: SIRT4 (Sirtuin 4 (SIRT4))

Autre désignation: SIRT4

Sujet:

Background: Sirtuin 4, also known as SIRT4, is a protein which in humans is encoded by the SIRT4 gene. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Gene Full Name: sirtuin 4

ID gène: 23409

UniProt: Q9Y6E7

Pathways: Negative Regulation of Hormone Secretion