SIVA1 anticorps (AA 1-141) (Biotin)

N° du produit ABIN8037860

Cet anticorps Lapin Polyclonal détecte spécifiquement SIVA1 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SIVA1 anticorps (AA 1-141) (Biotin) (ABIN8037860)

Antigène: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIVA1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SIVA1 anticorps (Biotin)

Épitope: AA 1-141

Fonction: Anti-SIVA/SIVA1 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SIVA/SIVA1 recombinant protein (Position: M1-T141).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SIVA1

Antigène: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Autre désignation: SIVA1

Sujet:

Background: Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene. This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis.

Gene Full Name: SIVA1 apoptosis inducing factor

ID gène: 10572

UniProt: O15304

Pathways: Positive Regulation of Endopeptidase Activity