SNAIL anticorps (AA 1-170) (Cy3)
Aperçu rapide pour SNAIL anticorps (AA 1-170) (Cy3) (ABIN8038568)
Antigène
Voir toutes SNAIL (SNAI1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-170
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Fonction
- Anti-SNAIL/SNAI1 Antibody Cy3 Conjugated
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human SNAIL/SNAI1 recombinant protein (Position: M1-K170).
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Isotype
- IgG
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Indications d'application
- Flow Cytometry, 1-3 μg/1x106 cells
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Date de péremption
- 12 months
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- SNAIL (SNAI1)
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Autre désignation
- SNAI1
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Sujet
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Background: The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.
Gene Full Name: snail family transcriptional repressor 1
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ID gène
- 6615
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UniProt
- O95863
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Antigène
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