SNX15 anticorps (AA 8-327) (Fluoro488)

N° du produit ABIN8040922

Cet anticorps anti-SNX15 Polyclonal Lapin conjugué à Fluoro488 (ABIN8040922) détecte spécifiquement SNX15 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SNX15 anticorps (AA 8-327) (Fluoro488) (ABIN8040922)

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX15 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-SNX15 anticorps (Fluoro488)

Épitope: AA 8-327

Fonction: Anti-SNX15 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SNX15 recombinant protein (Position: D8-K327).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SNX15

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Autre désignation: SNX15

Sujet:

Background: Sorting nexin-15 is a protein that in humans is encoded by the SNX15 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Gene Full Name: sorting nexin 15

ID gène: 29907

UniProt: Q9NRS6