SNX15 anticorps (AA 8-327)
Aperçu rapide pour SNX15 anticorps (AA 8-327) (ABIN8040930)
Antigène
Voir toutes SNX15 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Épitope
- AA 8-327
-
Fonction
- Anti-SNX15 Antibody
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins.
-
Attributs du produit
- Anti-SNX15 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E.coli-derived human SNX15 recombinant protein (Position: D8-K327).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
-
-
- SNX15 (Sorting Nexin 15 (SNX15))
-
Autre désignation
- SNX15
-
Sujet
-
Background: Sorting nexin-15 is a protein that in humans is encoded by the SNX15 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
Gene Full Name: sorting nexin 15
-
Poids moléculaire
- 50 kDa
-
ID gène
- 29907
-
UniProt
- Q9NRS6
Antigène
-