SP1 anticorps (C-Term) (HRP)

N° du produit ABIN8041093

Cet anticorps anti-SP1 Polyclonal Lapin conjugué à HRP (ABIN8041093) détecte spécifiquement SP1 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour SP1 anticorps (C-Term) (HRP) (ABIN8041093)

Antigène: SP1 (Sp1 Transcription Factor (SP1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SP1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-SP1 anticorps (HRP)

Épitope: C-Term

Fonction: Anti-Transcription factor Sp1 SP1 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse,rat sequences by two amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SP1, different from the related mouse and rat sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SP1

Antigène: SP1 (Sp1 Transcription Factor (SP1))

Autre désignation: SP1

Sujet:

Background: Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: Sp1 transcription factor

Sequence Similarities: Belongs to the Sp1 C2H2-type zinc-finger protein family.

UniProt: P08047

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction