SPAG7 anticorps (AA 1-199) (HRP)

N° du produit ABIN8041458

L’anticorps anti-SPAG7 Polyclonal Lapin est utilisé pour la détection de SPAG7 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour SPAG7 anticorps (AA 1-199) (HRP) (ABIN8041458)

Antigène: SPAG7 (Sperm Associated Antigen 7 (SPAG7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG7 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SPAG7 anticorps (HRP)

Épitope: AA 1-199

Fonction: Anti-SPAG7 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SPAG7 recombinant protein (Position: M1-D199).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SPAG7

Antigène: SPAG7 (Sperm Associated Antigen 7 (SPAG7))

Autre désignation: SPAG7

Sujet:

Background: Sperm-associated antigen 7 is a protein that in humans is encoded by the SPAG7 gene. SPAG7 (sperm-associated antigen 7) is a 227 amino acid nuclear protein that contains one R3H domain and is expressed in fetal brain. The gene that encodes SPAG7 consists of approximately 8,612 bases and maps to human chromosome 17p13.2. Encoding more than 1,200 genes, chromosome 17 comprises over 2.5 % of the human genome. 2 key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is ly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, colon, prostate gland and fallopian tubes.

Gene Full Name: sperm associated antigen 7

ID gène: 9552

UniProt: O75391