SPA17 anticorps (AA 1-136) (PE)

N° du produit ABIN8041482

L’anticorps anti-SPA17 Polyclonal Lapin est utilisé pour la détection de SPA17 dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour SPA17 anticorps (AA 1-136) (PE) (ABIN8041482)

Antigène: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPA17 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-SPA17 anticorps (PE)

Épitope: AA 1-136

Fonction: Anti-SPA17 Antibody PE Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SPA17 recombinant protein (Position: M1-K136). Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SPA17

Antigène: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Autre désignation: SPA17

Sujet:

Background: Sperm surface protein Sp17 is a protein that in humans is encoded by the SPA17 gene. This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

Gene Full Name: sperm autoantigenic protein 17

ID gène: 53340

UniProt: Q15506