SPATA18 anticorps (AA 27-490) (Fluoro594)

N° du produit ABIN8041545

L’anticorps anti-SPATA18 Polyclonal Lapin est utilisé pour la détection de SPATA18 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour SPATA18 anticorps (AA 27-490) (Fluoro594) (ABIN8041545)

Antigène: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPATA18 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-SPATA18 anticorps (Fluoro594)

Épitope: AA 27-490

Fonction: Anti-SPATA18 Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SPATA18 recombinant protein (Position: E27-R490).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SPATA18

Antigène: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Autre désignation: SPATA18

Sujet:

Background: This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.

Gene Full Name: spermatogenesis associated 18

ID gène: 132671

UniProt: Q8TC71