SMPD1 anticorps (AA 204-558) (Biotin)

N° du produit ABIN8041663

Cet anticorps anti-SMPD1 Polyclonal Lapin conjugué à Biotin (ABIN8041663) détecte spécifiquement SMPD1 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour SMPD1 anticorps (AA 204-558) (Biotin) (ABIN8041663)

Antigène: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMPD1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SMPD1 anticorps (Biotin)

Épitope: AA 204-558

Fonction: Anti-Smpd1 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Smpd1 recombinant protein (Position: D204-M558).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SMPD1

Antigène: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Autre désignation: Smpd1

Sujet:

Background: Sphingomyelin phosphodiesterase 1 (SMPD1), also known as acid sphingomyelinase (ASM), is an enzyme that in humans is encoded by the SMPD1 gene. Enables acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in ceramide biosynthetic process, positive regulation of apoptotic process, and response to ionizing radiation. Acts upstream of or within ceramide metabolic process, cholesterol metabolic process, and sphingomyelin catabolic process. Located in extracellular space. Is expressed in several structures, including alimentary system, integumental system, nervous system, sensory organ, and skeleton. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease, Niemann-Pick disease type A, and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1).

Gene Full Name: sphingomyelin phosphodiesterase 1, acid lysosomal

ID gène: 20597

UniProt: Q04519