SMPD1 anticorps (AA 204-558) (Fluoro550)
Aperçu rapide pour SMPD1 anticorps (AA 204-558) (Fluoro550) (ABIN8041666)
Antigène
Voir toutes SMPD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 204-558
-
Fonction
- Anti-Smpd1 Antibody Fluoro550 Conjugated
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E.coli-derived mouse Smpd1 recombinant protein (Position: D204-M558).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
Date de péremption
- 12 months
-
-
- SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
-
Autre désignation
- Smpd1
-
Sujet
-
Background: Sphingomyelin phosphodiesterase 1 (SMPD1), also known as acid sphingomyelinase (ASM), is an enzyme that in humans is encoded by the SMPD1 gene. Enables acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in ceramide biosynthetic process, positive regulation of apoptotic process, and response to ionizing radiation. Acts upstream of or within ceramide metabolic process, cholesterol metabolic process, and sphingomyelin catabolic process. Located in extracellular space. Is expressed in several structures, including alimentary system, integumental system, nervous system, sensory organ, and skeleton. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease, Niemann-Pick disease type A, and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1).
Gene Full Name: sphingomyelin phosphodiesterase 1, acid lysosomal
-
ID gène
- 20597
-
UniProt
- Q04519
Antigène
-