SKAP2 anticorps (AA 124-208) (Cy3)

N° du produit ABIN8042129

Cet anticorps Lapin Polyclonal détecte spécifiquement SKAP2 dans FACS. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour SKAP2 anticorps (AA 124-208) (Cy3) (ABIN8042129)

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKAP2 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-SKAP2 anticorps (Cy3)

Épitope: AA 124-208

Fonction: Anti-SKAP2 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SKAP2 recombinant protein (Position: E124-E208).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SKAP2

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Autre désignation: SKAP2

Sujet:

Background: Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene. The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: src kinase associated phosphoprotein 2

ID gène: 8935

UniProt: O75563