STARD10 anticorps (AA 1-273) (HRP)

N° du produit ABIN8042568

L’anticorps anti-STARD10 Polyclonal Lapin est utilisé pour la détection de STARD10 dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, WB et IHC.

Aperçu rapide pour STARD10 anticorps (AA 1-273) (HRP) (ABIN8042568)

Antigène: STARD10 (StAR-Related Lipid Transfer (START) Domain Containing 10 (STARD10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STARD10 est conjugé à/à la HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-STARD10 anticorps (HRP)

Épitope: AA 1-273

Fonction: Anti-PCTP-L/STARD10 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PCTP-L/STARD10 recombinant protein (Position: M1-E273).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur STARD10

Antigène: STARD10 (StAR-Related Lipid Transfer (START) Domain Containing 10 (STARD10))

Autre désignation: STARD10

Sujet:

Background: StAR-related lipid transfer protein 10 (STARD10) or PCTP-like protein is a lipid transfer protein that in humans is encoded by the STARD10 gene. StarD10 is a dual-specificity lipid transfer protein capable of shuttling phosphatidylcholine (PC) and phosphatidylethanolamine (PE) between membranes in vitro, changes in membrane composition of PC and PE occur before the morphological tumorigenic events. Interestingly, STARD10 has been described to be highly expressed in 35-40 % of ERBB2-positive breast cancers. StarD10 was initially discovered based on its cross-reactivity with a phosphoserine-specific antibody in mammary tumors from Neu/ErbB2 transgenic mice and subsequently isolated from SKBR3 human breast carcinoma cells using a multistep biochemical purification strategy. StarD10 contains a steroidogenic acute regulatory protein (StAR/StarD1)-related lipid transfer (START) domain that is thought to mediate binding of lipids. STARD10 is highly expressed in the liver and has been shown to transfer phosphatidylcholine.

Gene Full Name: StAR related lipid transfer domain containing 10

ID gène: 10809

UniProt: Q9Y365