STRADB anticorps (AA 24-411) (Fluoro647)

N° du produit ABIN8042682

L’anticorps anti-STRADB Polyclonal Lapin est utilisé pour la détection de STRADB dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour STRADB anticorps (AA 24-411) (Fluoro647) (ABIN8042682)

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRADB est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-STRADB anticorps (Fluoro647)

Épitope: AA 24-411

Fonction: Anti-STRADB Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human STRADB recombinant protein (Position: E24-E411).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur STRADB

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Autre désignation: STRADB

Sujet:

Background: STE20-related kinase adapter protein beta is an enzyme that in humans is encoded by the STRADB gene. This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: STE20 related adaptor beta

ID gène: 55437

UniProt: Q9C0K7

Pathways: AMPK Signaling