STRIP2 anticorps (AA 173-507)
Aperçu rapide pour STRIP2 anticorps (AA 173-507) (ABIN8043038)
Antigène
Voir toutes STRIP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 173-507
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Fonction
- Anti-FAM40B/STRIP2 Antibody
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Homologie
- Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.
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Attributs du produit
- Anti-FAM40B/STRIP2 Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human FAM40B/STRIP2 recombinant protein (Position: H173-Q507). Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- STRIP2 (Striatin Interacting Protein 2 (STRIP2))
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Autre désignation
- STRIP2
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Sujet
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Background: The STRIP2 gene encodes a protein known as striatin-interacting protein 2, which interacts with striatin, a scaffolding protein involved in diverse cellular processes such as signaling, cell adhesion, and transcriptional regulation. STRIP2 is implicated in cardiac development and function, where it modulates cardiac hypertrophy, contractility, and arrhythmogenesis. Additionally, it plays roles in neuronal development and synaptic plasticity in the brain. Dysregulation of STRIP2 expression or function has been associated with various cardiovascular disorders, including hypertrophic cardiomyopathy and arrhythmias, as well as neurodevelopmental disorders such as autism spectrum disorders. Elucidating the molecular mechanisms underlying STRIP2 function is essential for understanding its physiological roles in cardiac and neural tissues and its potential implications for disease pathology and therapeutic targeting.
Gene Full Name: striatin interacting protein 2
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Poids moléculaire
- 100 kDa
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ID gène
- 57464
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UniProt
- Q9ULQ0
Antigène
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