SYCP3 anticorps (AA 18-223) (Fluoro647)

N° du produit ABIN8044349

Cet anticorps Lapin Polyclonal détecte spécifiquement SYCP3 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SYCP3 anticorps (AA 18-223) (Fluoro647) (ABIN8044349)

Antigène: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYCP3 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-SYCP3 anticorps (Fluoro647)

Épitope: AA 18-223

Fonction: Anti-SCP3/SYCP3 Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human SCP3 shares 72%,73% amino acid (aa) sequences identity with mouse,rat SCP3,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SCP3 recombinant protein (Position: E18-E223). Human SCP3 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat SCP3, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SYCP3

Antigène: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Autre désignation: SYCP3

Sujet:

Background: SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.

Gene Full Name: synaptonemal complex protein 3

ID gène: 50511

UniProt: Q8IZU3