TRIM25 anticorps (AA 531-630)

N° du produit ABIN754858

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIM25 dans WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour TRIM25 anticorps (AA 531-630) (ABIN754858)

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM25 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TRIM25 anticorps

Épitope: AA 531-630

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRIM25

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TRIM25

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Autre désignation: TRIM25

Sujet:

Synonyms: EFP, Z147, RNF147, ZNF147, E3 ubiquitin/ISG15 ligase TRIM25, Estrogen-responsive finger protein, RING finger protein 147, Tripartite motif-containing protein 25, Ubiquitin/ISG15-conjugating enzyme TRIM25, Zinc finger protein 147, TRIM25

Background: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

ID gène: 7706

UniProt: Q14258