TJP1 anticorps (AA 1178-1527) (Fluoro488)

N° du produit ABIN8046744

L’anticorps anti-TJP1 Monoclonal Souris est utilisé pour la détection de TJP1 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour TJP1 anticorps (AA 1178-1527) (Fluoro488) (ABIN8046744)

Antigène: TJP1 (Tight Junction Protein 1 (TJP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TJP1 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Clone: 3E12

Détail du produit anti-TJP1 anticorps (Fluoro488)

Épitope: AA 1178-1527

Fonction: Anti-TJP1 Antibody (monoclonal, 3E12) Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TJP1 recombinant protein (Position: H1178-F1527). Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TJP1

Antigène: TJP1 (Tight Junction Protein 1 (TJP1))

Autre désignation: TJP1

Sujet:

Background: Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: tight junction protein 1

UniProt: Q07157

Pathways: Carbohydrate Homeostasis, Cell-Cell Junction Organization