TFPI2 anticorps (AA 70-105) (Biotin)

N° du produit ABIN8046962

Cet anticorps Lapin Polyclonal détecte spécifiquement TFPI2 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour TFPI2 anticorps (AA 70-105) (Biotin) (ABIN8046962)

Antigène: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFPI2 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-TFPI2 anticorps (Biotin)

Épitope: AA 70-105

Fonction: Anti-TFPI2 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TFPI2 recombinant protein (Position: E70-Q105).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TFPI2

Antigène: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Autre désignation: TFPI2

Sujet:

Background: Tissue factor pathway inhibitor 2, also known as TFPI2, is a human gene which is located at 7q22. It is an important regulator of the extrinsic pathway of blood coagulation through its ability to inhibit factor Xa and factor VIIa-tissue factor activity. After a 22-residue signal peptide, the mature TFPI2 protein contains 213 amino acids with 18 cysteines and 2 canonical N-linked glycosylation sites. The purified recombinant TFPI2 strongly inhibited the amidolytic activities of trypsin and the factor VIIa-tissue factor complex. The latter inhibition was markedly enhanced in the presence of heparin. Mouse TFPI2 mRNA is highly expressed in developing mouse placenta, as in human. And there are also high transcript levels in adult mouse liver and kidney.

Gene Full Name: tissue factor pathway inhibitor 2

ID gène: 7980

UniProt: P48307