STING/TMEM173 anticorps (C-Term) (Fluoro647)

N° du produit ABIN8049062

Cet anticorps Lapin Polyclonal détecte spécifiquement STING/TMEM173 dans FACS. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour STING/TMEM173 anticorps (C-Term) (Fluoro647) (ABIN8049062)

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STING/TMEM173 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-STING/TMEM173 anticorps (Fluoro647)

Épitope: C-Term

Fonction: Anti-TMEM173 Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by five amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human TMEM173, different from the related mouse sequence by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur STING/TMEM173

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Autre désignation: TMEM173

Sujet:

Background: Transmembrane protein 173 is a protein that in humans is encoded by the TMEM173 gene. This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. Also the encoded protein has been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Gene Full Name: stimulator of interferon response cGAMP interactor 1

Sequence Similarities: Belongs to the transcription factor STAT family.

ID gène: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response