STING/TMEM173 anticorps (C-Term)

N° du produit ABIN8049063

L’anticorps anti-STING/TMEM173 Polyclonal Lapin est utilisé pour la détection de STING/TMEM173 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC et FACS.

Aperçu rapide pour STING/TMEM173 anticorps (C-Term) (ABIN8049063)

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STING/TMEM173 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-STING/TMEM173 anticorps

Épitope: C-Term

Fonction: Anti-TMEM173 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by five amino acids.

Attributs du produit: Anti-TMEM173 Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human TMEM173, different from the related mouse sequence by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur STING/TMEM173

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Autre désignation: TMEM173

Sujet:

Background: Transmembrane protein 173 is a protein that in humans is encoded by the TMEM173 gene. This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. Also the encoded protein has been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Gene Full Name: stimulator of interferon response cGAMP interactor 1

Sequence Similarities: Belongs to the transcription factor STAT family.

Poids moléculaire: 35 kDa

ID gène: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response