CREM anticorps (AA 251-361) (Biotin)

N° du produit ABIN755364

Cet anticorps anti-CREM est un anticorps Lapin Polyclonal détectant CREM dans ELISA, IHC (fro) et IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour CREM anticorps (AA 251-361) (Biotin) (ABIN755364)

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREM est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CREM anticorps (Biotin)

Épitope: AA 251-361

Réactivité croisée: Humain, Souris

Homologie: Rat,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CREM

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CREM

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Autre désignation: CREM

Sujet:

Synonyms: cAMP response element modulator, CREM-1, cAMP responsive element modulator, hCREM 2, hCREM2, ICER, Inducible cAMP early repressor, Inducible cAMP early repressor ICER, MGC111110, MGC17881, MGC41893.

Background: CREM is a a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is derived from a multiexonic gene that encodes both activators and antagonists of cAMP-inducible transcription by differential splicing. Splice variants with antagonistic function lack 2 glutamine-rich domains and block cAMP-induced transcription, whereas an isoform that includes these glutamine-rich domains is a transcriptional activator.

ID gène: 1390

UniProt: Q03060

Pathways: Retinoic Acid Receptor Signaling Pathway