TSG101 anticorps (C-Term) (PE)

N° du produit ABIN8051696

Cet anticorps Lapin Polyclonal détecte spécifiquement TSG101 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TSG101 anticorps (C-Term) (PE) (ABIN8051696)

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSG101 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-TSG101 anticorps (PE)

Épitope: C-Term

Fonction: Anti-TSG101 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human TSG101, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TSG101

Sujet:

Background: TSG101, known as Tumor susceptibility gene 101, is mapped to 11p15. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. And the protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

Gene Full Name: tumor susceptibility 101

Sequence Similarities: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

ID gène: 7251

UniProt: Q99816