RENT2/UPF2 anticorps (AA 200-651) (PE)

N° du produit ABIN8052870

L’anticorps anti-RENT2/UPF2 Polyclonal Lapin est utilisé pour la détection de RENT2/UPF2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour RENT2/UPF2 anticorps (AA 200-651) (PE) (ABIN8052870)

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RENT2/UPF2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-RENT2/UPF2 anticorps (PE)

Épitope: AA 200-651

Fonction: Anti-hUPF2/RENT2/UPF2 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human hUPF2/RENT2/UPF2 recombinant protein (Position: K200-H651).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RENT2/UPF2

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Autre désignation: UPF2

Sujet:

Background: Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.

Gene Full Name: UPF2 regulator of nonsense mediated mRNA decay

ID gène: 26019

UniProt: Q9HAU5