VNN1 anticorps (AA 22-192) (Fluoro550)

N° du produit ABIN8053338

L’anticorps anti-VNN1 Polyclonal Lapin est utilisé pour la détection de VNN1 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour VNN1 anticorps (AA 22-192) (Fluoro550) (ABIN8053338)

Antigène: VNN1 (Vanin 1 (VNN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VNN1 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-VNN1 anticorps (Fluoro550)

Épitope: AA 22-192

Fonction: Anti-VNN1 Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: coli-derived human VNN1 recombinant protein (Position: Q22-K192). Human VNN1 shares 82.2% amino acid (aa) sequence identity with mouse VNN1.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human VNN1 recombinant protein (Position: Q22-K192). Human VNN1 shares 82.2% amino acid (aa) sequence identity with mouse VNN1.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur VNN1

Antigène: VNN1 (Vanin 1 (VNN1))

Autre désignation: VNN1

Sujet:

Background: Pantetheinase is an enzyme that in humans is encoded by the VNN1 gene. This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.

Gene Full Name: vanin 1

ID gène: 8876

UniProt: O95497

Pathways: Negative Regulation of intrinsic apoptotic Signaling