Vinculin anticorps (AA 930-1134) (APC)

N° du produit ABIN8053683

L’anticorps anti-Vinculin Polyclonal Lapin est utilisé pour la détection de Vinculin dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour Vinculin anticorps (AA 930-1134) (APC) (ABIN8053683)

Antigène: Vinculin (VCL)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vinculin est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-Vinculin anticorps (APC)

Épitope: AA 930-1134

Fonction: Anti-Vinculin/VCL Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human Vinculin shares 87.7% amino acid (aa) sequence identity with both mouse,rat Vinculin.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Vinculin recombinant protein (Position: E930-Q1134). Human Vinculin shares 87.7% amino acid (aa) sequence identity with both mouse and rat Vinculin.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Vinculin

Antigène: Vinculin (VCL)

Autre désignation: VCL

Sujet:

Background: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Gene Full Name: vinculin

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2