Exendin 4 anticorps

N° du produit ABIN8065456

Cet anticorps anti-Exendin 4 Monoclonal Souris (Clone 24) (ABIN8065456) détecte spécifiquement Exendin 4 dans ELISA. L’anticorps est réactif avec des échantillons de Gila monster.

Aperçu rapide pour Exendin 4 anticorps (ABIN8065456)

Antigène: Exendin 4

Reactivité: Gila monster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Exendin 4 est non-conjugé

Application: ELISA

Classe de qualité: Carrier-free

Clone: 24

Détail du produit anti-Exendin 4 anticorps

Fonction: Anti-Exendin-4 Antibody

Specificité: Specific for exendin-4. No cross-reactivity with GLP-1, GLP-2 (human) or glucagon coated on ELISA wells. The epitope is in the 9-39 region of the peptide, and the antibody cross-reacts strongly with exendin (9-39)amide.

Homologie: Gila monster Heloderma suspectum

Purification: Protein A or Protein G purified

Immunogène: Synthetic exendin-4

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C without exposure to light

Date de péremption: 24 months

Détails sur Exendin 4

Antigène: Exendin 4

Autre désignation: Exendin-4

Sujet: Exenatide,Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.,N/A,Exendin-4 is a 39 amino acid peptide found in venom from the Gila monster Heloderma suspectum. It is a member of the glucagon-secretin family of peptide hormones and neuropeptides. Exendin-4 is a potent agonist of the GLP-1 receptor and hence a potent stimulator of insulin secretion.

Poids moléculaire: 4.2 kDa

UniProt: P26349