Peptide YY anticorps (N-Term)
Aperçu rapide pour Peptide YY anticorps (N-Term) (ABIN8065519)
Antigène
Voir toutes Peptide YY (PYY) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- N-Term
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Fonction
- Anti-PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) Antibody
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Specificité
- ABIN8065519 binds human PYY(3-36). Based on inhibition ELISA, ABIN8065519 shows no cross-reaction with PYY(1-36) or NPY. The epitope lies within residues 3-12 of human PYY.
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Homologie
- Human
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Purification
- Protein A or Protein G purified
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Immunogène
- Synthetic N-terminal fragment of human PYY(3-36) coupled to carrier.
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Isotype
- IgG2a, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C without exposure to light
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Date de péremption
- 24 months
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- Peptide YY (PYY)
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Autre désignation
- PYY
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Sujet
- PYY, PYY-I, PYY1, peptide YY, peptide tyrosine tyrosine, prepro-PYY,This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.,PYY,Peptide tyrosine-tyrosine amide (3-36), or PYY(3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY(3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY(3-36) is additive to that of the co-secreted gut hormone GLP-1.
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Poids moléculaire
- 4 kDa
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ID gène
- 5697
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UniProt
- P10082
Antigène
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