Vitronectin anticorps

N° du produit ABIN8065534

Cet anticorps anti-Vitronectin Monoclonal Souris (Clone HV23) (ABIN8065534) détecte spécifiquement Vitronectin dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Vitronectin anticorps (ABIN8065534)

Antigène: Vitronectin (VTN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Vitronectin est non-conjugé

Application: Western Blotting (WB), ELISA

Classe de qualité: Carrier-free

Clone: HV23

Détail du produit anti-Vitronectin anticorps

Fonction: Anti-Vitronectin Antibody

Specificité: CSI 003-23 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 003-23 binds nearly as well to native vitronectin as to denatured. CSI 003-23 is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding. Epitope is located in the somatomedin B domain

Homologie: Canine,Feline,Goat,Horse,and Human

Purification: Protein A or Protein G purified

Immunogène: Human vitronectin purified from plasma by heparin-affinity chromatography

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C without exposure to light

Date de péremption: 24 months

Détails sur Vitronectin

Antigène: Vitronectin (VTN)

Autre désignation: Vitronectin

Sujet: VTN, V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B,Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway., Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.,VTN,Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin. (2)

Poids moléculaire: 65 kDa, 75 kDA

ID gène: 7448

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration