Vitronectin anticorps

N° du produit ABIN8065535

Cet anticorps Souris Monoclonal détecte spécifiquement Vitronectin dans IHC, ELISA et AP. Il présente une réactivité avec des échantillons de Boeuf (Vache).

Aperçu rapide pour Vitronectin anticorps (ABIN8065535)

Antigène: Vitronectin (VTN)

Reactivité: Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Vitronectin est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Affinity Purification (AP)

Classe de qualité: Carrier-free

Clone: A18

Détail du produit anti-Vitronectin anticorps

Fonction: Anti-Vitronectin Antibody

Specificité: CSI 004-18 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). The antibody inhibits integrin-mediated cell adhesion to bovine vitronectin. It can be used to probe vitronectin conformation.

Homologie: Bovine,Horse,and Rabbit

Purification: Protein A or Protein G purified

Immunogène: Lysed bovine corneal endothelial cells and extracellular matrix

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C without exposure to light

Date de péremption: 24 months

Détails sur Vitronectin

Antigène: Vitronectin (VTN)

Autre désignation: Vitronectin

Sujet: VTN, V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B,Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway., Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.,VTN,Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin.

Poids moléculaire: 65 kDa, 75 kDA

ID gène: 507525

UniProt: Q3ZBS7

Pathways: Autophagy, Smooth Muscle Cell Migration