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CDC6 anticorps (pSer54)

Cet anticorps Lapin Polyclonal détecte spécifiquement CDC6 dans WB, ELISA, IHC (p), IF (p), IF (cc) et IHC (fro). Il présente une réactivité envers Humain.
N° du produit ABIN756997

Aperçu rapide pour CDC6 anticorps (pSer54) (ABIN756997)

Antigène

Voir toutes CDC6 Anticorps
CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Reactivité

  • 87
  • 24
  • 17
  • 4
  • 1
Humain

Hôte

  • 78
  • 8
  • 1
Lapin

Clonalité

  • 70
  • 17
Polyclonal

Conjugué

  • 39
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CDC6 est non-conjugé

Application

  • 58
  • 35
  • 26
  • 11
  • 9
  • 8
  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    • 20
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer54

    Homologie

    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic phosphopeptide derived from human Cdc6 around the phosphorylation site of Ser54 [PL(p-S)PR]

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • Antigène

    CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

    Autre désignation

    Cdc6

    Sujet

    Synonyms: Cell Division Cycle protein 6, Cdc 18L, Cdc 6, CDC18 cell division cycle 18, S.pombe, homolog like, CDC18 S.pombe, CDC18 like, CDC18S.pombe, Cdc18L, CDC6 related protein, Cdc6p, Cell cycle controller, Cell division control protein 6, Cell division control protein 6 homolog, Cell division cycle 18, Cell division cycle 18 homolog, Cell division cycle 6 homolog, Cell division cycle 6 protein, HsCDC 18, HsCDC 6, HsCDC18, HsCDC6, p62, p62cdc 6, p62cdc6, CDC6_HUMAN.

    Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

    ID gène

    990

    Pathways

    DNA Replication, Synthesis of DNA
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