CDC6 anticorps (pSer54)
Aperçu rapide pour CDC6 anticorps (pSer54) (ABIN756997)
Antigène
Voir toutes CDC6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer54
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Homologie
- Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Cdc6 around the phosphorylation site of Ser54 [PL(p-S)PR]
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
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Autre désignation
- Cdc6
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Sujet
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Synonyms: Cell Division Cycle protein 6, Cdc 18L, Cdc 6, CDC18 cell division cycle 18, S.pombe, homolog like, CDC18 S.pombe, CDC18 like, CDC18S.pombe, Cdc18L, CDC6 related protein, Cdc6p, Cell cycle controller, Cell division control protein 6, Cell division control protein 6 homolog, Cell division cycle 18, Cell division cycle 18 homolog, Cell division cycle 6 homolog, Cell division cycle 6 protein, HsCDC 18, HsCDC 6, HsCDC18, HsCDC6, p62, p62cdc 6, p62cdc6, CDC6_HUMAN.
Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
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ID gène
- 990
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Pathways
- DNA Replication, Synthesis of DNA
Antigène
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