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CASC3 anticorps (pTyr181) (Biotin)

CASC3 Reactivité: Souris WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN757554
  • Antigène Voir toutes CASC3 Anticorps
    CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
    Épitope
    • 15
    • 15
    • 9
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    pTyr181
    Reactivité
    • 46
    • 35
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 74
    • 1
    Lapin
    Clonalité
    • 75
    Polyclonal
    Conjugué
    • 26
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CASC3 est conjugé à/à la Biotin
    Application
    • 65
    • 28
    • 27
    • 26
    • 26
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human CASC3 around the phosphorylation site of Tyr181
    Isotype
    IgG
    Top Product
    Discover our top product CASC3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
    Autre désignation
    CASC3 (CASC3 Produits)
    Synonymes
    anticorps BTZ, anticorps MLN51, anticorps Btz, anticorps Mln51, anticorps CASC3, anticorps btz, anticorps mln51, anticorps StMLN51, anticorps barentsz, anticorps XlMLN51, anticorps cancer susceptibility 3, anticorps cancer susceptibility candidate 3, anticorps protein CASC3, anticorps cancer susceptibility 3 S homeolog, anticorps CASC3, anticorps Casc3, anticorps casc3, anticorps casc3.S
    Sujet

    Synonyms: Barentsz protein, Btz, Cancer susceptibility candidate gene 3 protein, Metastatic lymph node protein 51, MLN 51 protein, MLN51, Protein barentsz, Protein CASC3, Protein MLN 51, CASC3_HUMAN.

    Background: The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exonexon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh and Y14, the human homologs of mago nashi and tsunagi, are core components of the exon junction complex (EJC). The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, and translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.

    ID gène
    22794
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