P4HTM anticorps (AA 201-300)

N° du produit ABIN759521

L’anticorps Lapin Polyclonal anti-P4HTM a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter P4HTM dans des échantillons de Humain.

Aperçu rapide pour P4HTM anticorps (AA 201-300) (ABIN759521)

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P4HTM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-P4HTM anticorps

Épitope: AA 201-300

Homologie: Human,Mouse,Rat,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HIFPH4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur P4HTM

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Autre désignation: HPH4

Sujet:

Synonyms: EGLN4, H prolyl hydroxylase PH4, H-PH4, H-prolyl hydroxylase 4, HPH4, HPH-4, Hypoxia inducible factor prolyl 4 hydroxylase, Hypoxia inducible factor prolyl hydroxylase, Hypoxia-inducible factor prolyl hydroxylase 4, P4H TM, P4H with transmembrane domain, P4H-TM, P4htm, P4HTM_HUMAN, PH 4, PH4, PHD4, Proline 4 hydroxylase, Prolyl 4 hydroxylase transmembrane endoplasmic reticulum, Prolyl hydroxlase domain containing 4, Transmembrane prolyl 4-hydroxylase.

Background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.