P4HTM anticorps (AA 201-300) (Biotin)

N° du produit ABIN759523

Cet anticorps Lapin Polyclonal détecte spécifiquement P4HTM dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour P4HTM anticorps (AA 201-300) (Biotin) (ABIN759523)

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P4HTM est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-P4HTM anticorps (Biotin)

Épitope: AA 201-300

Homologie: Human,Mouse,Rat,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HIFPH4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur P4HTM

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Autre désignation: HPH4

Sujet:

Synonyms: EGLN4, H prolyl hydroxylase PH4, H-PH4, H-prolyl hydroxylase 4, HPH4, HPH-4, Hypoxia inducible factor prolyl 4 hydroxylase, Hypoxia inducible factor prolyl hydroxylase, Hypoxia-inducible factor prolyl hydroxylase 4, P4H TM, P4H with transmembrane domain, P4H-TM, P4htm, P4HTM_HUMAN, PH 4, PH4, PHD4, Proline 4 hydroxylase, Prolyl 4 hydroxylase transmembrane endoplasmic reticulum, Prolyl hydroxlase domain containing 4, Transmembrane prolyl 4-hydroxylase.

Background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.