ANGPTL3 anticorps (AA 21-120)

N° du produit ABIN759806

L’anticorps Lapin Polyclonal anti-ANGPTL3 a été validé pour WB et ELISA. Il convient pour détecter ANGPTL3 dans des échantillons de Humain.

Aperçu rapide pour ANGPTL3 anticorps (AA 21-120) (ABIN759806)

Antigène: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANGPTL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ANGPTL3 anticorps

Épitope: AA 21-120

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ANGPTL3

Antigène: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Autre désignation: ANGPTL3

Sujet:

Synonyms: ANL3, ANG-5, FHBL2, ANGPT5, Angiopoietin-related protein 3, Angiopoietin-5, Angiopoietin-like protein 3, ANGPTL3, UNQ153/PRO179

Background: Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.

ID gène: 27329

UniProt: Q9Y5C1