SERINC3 anticorps (PE)
Aperçu rapide pour SERINC3 anticorps (PE) (ABIN760161)
Antigène
Voir toutes SERINC3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Souris
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Homologie
- Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human SERINC3
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- SERINC3 (Serine Incorporator 3 (SERINC3))
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Autre désignation
- SERINC3
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Sujet
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Synonyms: TMS 1, TMS-1, AIGP1, DF33, SBBI99, serine incorporator 3, TDE, TDE1, Tumor dferentially expressed protein 1, SERC3_HUMAN.
Background: TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
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Poids moléculaire
- 53kDa
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ID gène
- 10955
Antigène
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