SALL3 anticorps (N-Term)

N° du produit ABIN8111107

Cet anticorps Lapin Polyclonal détecte spécifiquement SALL3 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SALL3 anticorps (N-Term) (ABIN8111107)

Antigène: SALL3 (Sal-Like 3 (SALL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SALL3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SALL3 anticorps

Épitope: N-Term

Fonction: SALL3 Antibody - N-terminal region

Séquence: MSRRKQAKPQ HLKSDEELLP PDGAPEHAAP GEGAEDADSG PESRSGGEET

Homologie: Cow: 79%, Dog: 79%, Human: 100%, Mouse: 100%, Pig: 85%, Rat: 100%, Zebrafish: 93%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SALL3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39971-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SALL3

Antigène: SALL3 (Sal-Like 3 (SALL3))

Autre désignation: SALL3

Sujet:

Background Information: This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.

Gene Name: spalt like transcription factor 3

Alternative Symbols: ZNF796

Protein Name: Sal-like protein 3

Poids moléculaire: 143 kDa

ID gène: 27164

NCBI Accession: NP_741996

UniProt: Q9BXA9