Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CTCFL anticorps (AA 351-450)

CTCFL Reactivité: Humain WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN760421
  • Antigène Voir toutes CTCFL Anticorps
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    Épitope
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivité
    • 27
    • 11
    • 3
    Humain
    Hôte
    • 30
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 31
    • 2
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTCFL est non-conjugé
    Application
    • 27
    • 12
    • 12
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human BORIS/CT27
    Isotype
    IgG
    Top Product
    Discover our top product CTCFL Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    Autre désignation
    Ct27 (CTCFL Produits)
    Synonymes
    anticorps BORIS, anticorps CT27, anticorps CTCF-T, anticorps HMGB1L1, anticorps dJ579F20.2, anticorps CTCFL, anticorps Boris, anticorps OTTMUSG00000016680, anticorps CCCTC-binding factor like, anticorps CCCTC-binding factor (zinc finger protein)-like, anticorps CTCFL, anticorps Ctcfl
    Sujet

    Synonyms: BORIS like protein, Brother of the regulator of imprinted sites, Cancer/testis antigen 27, CCCTC binding factor zinc finger protein like, CCCTC-binding factor, CT27, CTCF paralog, CTCF T, CTCF-like protein, CTCFL, CTCFL_HUMAN, HMG 1L1, HMGB1L1, Putative high mobility group protein 1 like 1, Putative high mobility group protein B1 like 1, Transcriptional repressor CTCFL, Zinc finger protein CTCF-T.

    Background: Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.

    ID gène
    140690
Vous êtes ici:
Support technique