CDCA7L anticorps (AA 381-454) (Biotin)

N° du produit ABIN760438

Cet anticorps Lapin Polyclonal détecte spécifiquement CDCA7L dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CDCA7L anticorps (AA 381-454) (Biotin) (ABIN760438)

Antigène: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDCA7L est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CDCA7L anticorps (Biotin)

Épitope: AA 381-454

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CDCA7L

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CDCA7L

Antigène: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Autre désignation: CDCA7L

Sujet:

Synonyms: c Myc Interacting protein JPO2, DKFZp762L0311, RAM2, HR1, JPO2, Protein JPO2, R1 antibody Transcription Factor RAM2.CDA7L_HUMAN

Background: CDCA7L is a member of the CDCA (cell division cycle associated) protein family. Members of this family have expression patterns associated with other known cell cycle genes such as cyclins and CDC genes. CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It is involved in apoptotic signaling pathways and may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

ID gène: 55536